Not known Factual Statements About Ocifisertib(CFI-400945 free base)
PKA phosphorylates Myosin Binding Protein-C (MyBP-C) and troponin I (TnI) inside the cardiac myofibril. TnI could be the inhibitory part with the trimeric troponin molecule which makes up the Ca2+-change from the contractile apparatus. TnI binds to TnC when Ca2+ is sure to TnC, although during the absence of Ca2+, the C-terminus of TnI is produced